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DTI Methods To Avoid

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Beware of These DTI Methods That Can Compromise Your Case

When used correctly, DTI exams can reliably identify Traumatic Brain Injuries in cases where CT and MRI exam results have been described as normal. But some DTI providers are still using methods that have proven problematic in court. Below are four common methods some DTI providers are using that can actually harm your case instead of advancing it.

  1. Reject Mesmerizing DTI Tractography: Visual inspection of white matter fiber tracts by a neuroradiologist for pre-surgical planning is not useful for evaluating TBI. The examiners use their subjective judgement to determine if tracts look abnormal and typically provide no quantitative analysis. The tracts are subjectively “drawn” and frequently by MRI technologists.
  2. Asymmetry Analyses Are Faulty: These analyses are based on the principle that the brain demonstrates a high level of bi-fold symmetry and that injury causes asymmetry. Unfortunately, injuries can result in bilateral damage. Looking for Asymmetrical Fractional Anisotropy (FA) values does not provide normative data points for comparison.
  3. FA Values Published in Journals Are Inadequate: We don’t recommend comparing your client’s FA values to the various FA values that have been published in a variety of journals. In this scenario, your provider may try to determine whether your client’s FA values are normal based on data released in multiple peer-reviewed publications over time. Unfortunately, these data can vary widely based on MRI field strength, hardware, software, and sources for patient studies.
  4. Avoid Comparisons With a Small Collection of Data: Make sure your provider doesn’t attempt to compare your client’s FA values to the collective FA values of too few control subjects, without narrowing the comparison group to match your client’s age range and gender. Inevitably, these small datasets are statistically weak and provide insufficient power to support conclusions about an injury.

The Concussion Group strongly believes the proprietary Quantify database provides the most scientifically valid normative database for individual comparison. Other databases lack volume and integrity. Our large dataset allows individual exam results to be matched to a subset of age and sex-matched control subjects.

What Is the Source of the Control Data for The Concussion Group?

QuantifyTM analyses were developed by MINDSET Consulting Group in collaboration with attorneys who are experts in the admissibility of scientific evidence and neuroscientists who are experts in neuroimaging data analysis and neurobiology. Quantitative analysis of Fractional Anisotropy and comparison to large normative databases is now considered the gold standard in clinical and experimental research studies funded by the National Institutes of Health.

What Data Is Analyzed in a qDTI Exam?

Our qDTI exams rely on 1,200+ control datasets across 107 brain regions and 48 fiber tracts. We incorporate imaging sequences that collect high-resolution MRI data across the entire brain. The qDTI algorithms then extract detailed measurements of your client’s brain. QuantifyTM organizes the gray matter data measurements into 107 recognized brain regions and measures the integrity of 48 major white matter fiber tracts interconnecting different regions. A Volumetric Analysis studies the gray matter made up of cell bodies that act as the brain’s processing motors. A qDTI analysis studies the white matter fiber tracts that connect cell bodies and enable communication across brain regions.

How Your Client’s Data Is Compared To the Control Group

Our qDTI analysis relies on control datasets from calibrated scanners.
Each of the 1,200+ sets of brain measurements in the control group were collected on the same MRI scanner and with the same protocols. A unique scaling method calibrates the machine used for your client to the one that obtained the control dataset, thus eliminating the contentious issues of variability between individual scanners, manufacturers, and generic normative datasets.



About Diffusion Tensor Imaging

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Sample DTI Reports

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How To Prove TBI With qDTI

See the Guide


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  • Home
  • About
    • The Concussion Group
    • Locations
    • Team Members
  • DTI
    • Diffusion Tensor Imaging
    • DTI and Concussions
    • DTI Methods To Avoid
    • DTI Sample Reports
  • Lawyers
    • qDTI Exams for TBI
    • Advance Your TBI Case With qDTI
    • What To Expect From Us
    • Mindset
  • Contact Us
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